# LINEX2 python package
![PyPI - License](https://img.shields.io/pypi/l/linex2) ![PyPI](https://img.shields.io/pypi/v/linex2)
The software is the implementation for Lipid network computation and analysis
for the Lipid Network Explorer (LINEX) version 2.
The LINEX web service can be found here:
[https://exbio.wzw.tum.de/linex/](https://exbio.wzw.tum.de/linex/)
### Publication
If you use this package, please cite our publication:
Rose and Koehler et al. "**Lipid network and moiety analysis for revealing enzymatic dysregulation and mechanistic alterations from lipidomics data**",
_Briefings in Bioinformatics_ **2023**, bbac572; doi: [https://doi.org/10.1093/bib/bbac572](https://doi.org/10.1093/bib/bbac572)
### Data in package
The package includes data from the [Reactome](https://reactome.org/) and
[Rhea](https://www.rhea-db.org/) databases.
* **Rhea** data is available under the
[Creative Commons Attribution (CC BY 4.0) License](https://creativecommons.org/licenses/by/4.0/)
and is published here: Bansal et al. "Rhea, the reaction knowledgebase in 2022".
Nucleic Acids Res. (2021), DOI: [10.1093/nar/gkab1016](https://doi.org/10.1093/nar/gkab1016)
* **Reactome** data is available under the
[Creative Commons Public Domain (CC0) License](https://creativecommons.org/publicdomain/zero/1.0/)
and is published here: Jassal et al. "The reactome pathway knowledgebase".
Nucleic Acids Res. (2020), DOI: [10.1093/nar/gkz1031](https://doi.org/10.1093/nar/gkz1031)
### License
The software is published under the AGPLv3 license.
![AGPLv3 logo](https://www.gnu.org/graphics/agplv3-with-text-162x68.png)
The software includes code from the
* **Rhea** data is available under the
[Creative Commons Attribution (CC BY 4.0) License](https://creativecommons.org/licenses/by/4.0/)
and is published here: Bansal et al. "Rhea, the reaction knowledgebase in 2022".
Nucleic Acids Res. (2021), DOI: [10.1093/nar/gkab1016](https://doi.org/10.1093/nar/gkab1016)
* **Reactome** data is available under the
[Creative Commons Public Domain (CC0) License](https://creativecommons.org/publicdomain/zero/1.0/)
and is published here: Jassal et al. "The reactome pathway knowledgebase".
Nucleic Acids Res. (2020), DOI: [10.1093/nar/gkz1031](https://doi.org/10.1093/nar/gkz1031)
[LINEX webtool](https://gitlab.lrz.de/lipitum-projects/linex)
published under the same license and written by the same authors.
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"author": "Tim Daniel Rose, Nikolai Koehler, Olga Lazareva, Josch Konstantin Pauling",
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