Name | ap-features JSON |
Version |
2023.7.4
JSON |
| download |
home_page | |
Summary | Package to compute features of traces from action potential models |
upload_time | 2023-10-18 10:05:35 |
maintainer | |
docs_url | None |
author | |
requires_python | >=3.7 |
license | LGPL-2.1 |
keywords |
action potential
cell
models
features
|
VCS |
|
bugtrack_url |
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requirements |
No requirements were recorded.
|
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# Action Potential features
`ap_features` is package for computing features of action potential traces. This includes chopping, background correction and feature calculations.
Parts of this library is written in `numba` and is therefore highly performant. This is useful if you want to do feature calculations on a large number of traces.
## Quick start
```python
import matplotlib.pyplot as plt
import numpy as np
from scipy.integrate import solve_ivp
import ap_features as apf
time = np.linspace(0, 999, 1000)
res = solve_ivp(
apf.testing.fitzhugh_nagumo,
[0, 1000],
[0.0, 0.0],
t_eval=time,
)
trace = apf.Beats(y=res.y[0, :], t=time)
print(f"Number of beats: {trace.num_beats}")
print(f"Beat rates: {trace.beat_rates}")
# Get a list of beats
beats = trace.beats
# Pick out the second beat
beat = beats[1]
# Compute features
print(f"APD30: {beat.apd(30):.3f}s, APD80: {beat.apd(80):.3f}s")
print(f"cAPD30: {beat.capd(30):.3f}s, cAPD80: {beat.capd(80):.3f}s")
print(f"Time to peak: {beat.ttp():.3f}s")
print(f"Decay time from max to 90%: {beat.tau(a=0.1):.3f}s")
```
```
Number of beats: 5
Beat rates: [779.2207792207793, 769.2307692307693, 779.2207792207793, 759.493670886076]
APD30: 37.823s, APD80: 56.564s
cAPD30: 88.525s, cAPD80: 132.387s
Time to peak: 21.000s
Decay time from max to 90%: 53.618s
```
## Install
Install the package with pip
```
python -m pip install ap_features
```
See [installation instructions](https://computationalphysiology.github.io/ap_features/INSTALL.html) for more options.
## Available features
The list of currently implemented features are as follows
- Action potential duration (APD)
- Corrected action potential duration (cAPD)
- Decay time (Time for the signal amplitude to go from maximum to (1 - a) * 100 % of maximum)
- Time to peak (ttp)
- Upstroke time (time from (1-a)*100 % signal amplitude to peak)
- Beating frequency
- APD up (The duration between first intersections of two APD lines)
- Maximum relative upstroke velocity
- Maximum upstroke velocity
- APD integral (integral of the signals above the APD line)
## Documentation
Documentation is hosted at GitHub pages: <https://computationalphysiology.github.io/ap_features/>
Note that the documentation is written using [`jupyterbook`](https://jupyterbook.org) and contains an [interactive demo](https://computationalphysiology.github.io/ap_features/demo_fitzhugh_nagumo.html)
## License
* Free software: LGPLv2.1
## Source Code
* <https://github.com/ComputationalPhysiology/ap_features>
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"description": "[![image](https://img.shields.io/pypi/v/ap_features.svg)](https://pypi.python.org/pypi/ap_features)\n![CI](https://github.com/ComputationalPhysiology/ap_features/workflows/CI/badge.svg)\n[![pre-commit.ci status](https://results.pre-commit.ci/badge/github/ComputationalPhysiology/ap_features/main.svg)](https://results.pre-commit.ci/latest/github/ComputationalPhysiology/ap_features/main)\n[![github pages](https://github.com/ComputationalPhysiology/ap_features/actions/workflows/github-pages.yml/badge.svg)](https://github.com/ComputationalPhysiology/ap_features/actions/workflows/github-pages.yml)\n[![Build and upload to PyPI](https://github.com/ComputationalPhysiology/ap_features/actions/workflows/pypi.yml/badge.svg)](https://github.com/ComputationalPhysiology/ap_features/actions/workflows/pypi.yml)\n[![Coverage](https://img.shields.io/endpoint?url=https://gist.githubusercontent.com/finsberg/a7290de789564f03eb6b1ee122fce423/raw/ap_features-coverage.json)](https://img.shields.io/endpoint?url=https://gist.githubusercontent.com/finsberg/a7290de789564f03eb6b1ee122fce423/raw/ap_features-coverage.json)\n# Action Potential features\n\n`ap_features` is package for computing features of action potential traces. This includes chopping, background correction and feature calculations.\n\nParts of this library is written in `numba` and is therefore highly performant. This is useful if you want to do feature calculations on a large number of traces.\n\n## Quick start\n\n```python\nimport matplotlib.pyplot as plt\nimport numpy as np\nfrom scipy.integrate import solve_ivp\n\nimport ap_features as apf\n\ntime = np.linspace(0, 999, 1000)\nres = solve_ivp(\n apf.testing.fitzhugh_nagumo,\n [0, 1000],\n [0.0, 0.0],\n t_eval=time,\n)\ntrace = apf.Beats(y=res.y[0, :], t=time)\nprint(f\"Number of beats: {trace.num_beats}\")\nprint(f\"Beat rates: {trace.beat_rates}\")\n\n# Get a list of beats\nbeats = trace.beats\n# Pick out the second beat\nbeat = beats[1]\n\n# Compute features\nprint(f\"APD30: {beat.apd(30):.3f}s, APD80: {beat.apd(80):.3f}s\")\nprint(f\"cAPD30: {beat.capd(30):.3f}s, cAPD80: {beat.capd(80):.3f}s\")\nprint(f\"Time to peak: {beat.ttp():.3f}s\")\nprint(f\"Decay time from max to 90%: {beat.tau(a=0.1):.3f}s\")\n```\n\n```\nNumber of beats: 5\nBeat rates: [779.2207792207793, 769.2307692307693, 779.2207792207793, 759.493670886076]\nAPD30: 37.823s, APD80: 56.564s\ncAPD30: 88.525s, cAPD80: 132.387s\nTime to peak: 21.000s\nDecay time from max to 90%: 53.618s\n```\n\n## Install\nInstall the package with pip\n```\npython -m pip install ap_features\n```\nSee [installation instructions](https://computationalphysiology.github.io/ap_features/INSTALL.html) for more options.\n\n\n## Available features\nThe list of currently implemented features are as follows\n- Action potential duration (APD)\n- Corrected action potential duration (cAPD)\n- Decay time (Time for the signal amplitude to go from maximum to (1 - a) * 100 % of maximum)\n- Time to peak (ttp)\n- Upstroke time (time from (1-a)*100 % signal amplitude to peak)\n- Beating frequency\n- APD up (The duration between first intersections of two APD lines)\n- Maximum relative upstroke velocity\n- Maximum upstroke velocity\n- APD integral (integral of the signals above the APD line)\n\n\n## Documentation\nDocumentation is hosted at GitHub pages: <https://computationalphysiology.github.io/ap_features/>\n\nNote that the documentation is written using [`jupyterbook`](https://jupyterbook.org) and contains an [interactive demo](https://computationalphysiology.github.io/ap_features/demo_fitzhugh_nagumo.html)\n\n\n## License\n* Free software: LGPLv2.1\n\n## Source Code\n* <https://github.com/ComputationalPhysiology/ap_features>\n",
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