# cbgen
Python wrapper around a BGEN library.
([cbgen documentation](https://cbgen.readthedocs.io)).
[BGEN](https://www.well.ox.ac.uk/~gav/bgen_format/) is a file format for
storing large genetic datasets. It supports both unphased genotypes and phased
haplotype data with variable ploidy and number of alleles. It was designed to
provide a compact data representation without sacrificing variant access
performance. This Python package is a wrapper around the [bgen
library](https://github.com/limix/bgen), a low-memory footprint reader that
efficiently reads bgen files. It fully supports the bgen format specifications:
1.2 and 1.3; as well as their optional compressed formats.
## Installation
```bash
pip install cbgen
```
## Usage example
```python
>>> import cbgen
>>>
>>> bgen = cbgen.bgen_file(cbgen.example.get("haplotypes.bgen"))
>>> bgen.create_metafile("haplotypes.bgen.metafile")
>>> mf = cbgen.bgen_metafile("haplotypes.bgen.metafile")
>>> print(mf.npartitions)
1
>>> print(mf.nvariants)
4
>>> print(mf.partition_size)
4
>>> part = mf.read_partition(0)
>>> gt = bgen.read_genotype(part.variants.offset[0])
>>> print(gt.probability)
[[1. 0. 1. 0.]
[0. 1. 1. 0.]
[1. 0. 0. 1.]
[0. 1. 0. 1.]]
>>> mf.close()
>>> bgen.close()
```
## Authors
* [Carl Kadie](https://github.com/CarlKCarlK)
* [Danilo Horta](https://github.com/horta)
## License
This project is licensed under the [MIT License](https://raw.githubusercontent.com/limix/cbgen/main/LICENSE).
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