Name | inferploidy JSON |
Version |
0.3.3
JSON |
| download |
home_page | https://github.com/combio-dku |
Summary | Tookits for Tumor cell identification in single-cell RNA-seq data |
upload_time | 2025-07-15 05:09:01 |
maintainer | None |
docs_url | None |
author | Seokhyun Yoon |
requires_python | None |
license | MIT License
Copyright (c) 2024 Machine Learning & Bioinformatics Lab.
Permission is hereby granted, free of charge, to any person obtaining a copy
of this software and associated documentation files (the "Software"), to deal
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The above copyright notice and this permission notice shall be included in all
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THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
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AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM,
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SOFTWARE.
|
keywords |
single-cell omics
bioinformatics
|
VCS |
|
bugtrack_url |
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requirements |
No requirements were recorded.
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# InferPloidy
## Brief introduction
- InferPloidy is a CNV-based, ploidy annotation tool for single-cell RNA-seq data.
- It works with the CNV-estimates obtained from [infercnv](https://github.com/icbi-lab/infercnvpy) .
## Cite InferPloidy
- "InferPloidy: A fast ploidy inference tool accurately classifies cells with abnormal CNVs in large single-cell RNA-seq datasets", available at [bioRxiv](https://doi.org/10.1101/2025.03.13.643178)
<div align="center">
<img src="https://github.com/combio-dku/inferploidy/blob/main/images/inferploidy.png" style="width:80%;"/>
</div>
## Installation using pip, importing inferploidy in Python
InferPloidy can be installed using pip command. With python3 installed in your system, simply use the follwing command in a terminal.
`pip install inferploidy`
Once it is installed using pip, you can import two functions using the following python command.
`from inferploidy import run_infercnv, run_inferploidy`
## Example usage in Jupyter notebook
`inferPloidy_example.ipynb` is example code in Jupyter notebook, where you can see how to import and run InferPloidy.
To run HiCAT, you need the pre-installed python packages `numpy`, `pandas`, `scikit-learn`, `scipy`, `scikit-network`, `infercnvpy` and , `hicat`.
`hicat` is used to annotate cell-type to collect reference cells for infercnv.
All of them can be installed simply using `pip` command.
## Contact
Send email to syoon@dku.edu for any inquiry on the usages.
Raw data
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