inferploidy


Nameinferploidy JSON
Version 0.3.3 PyPI version JSON
download
home_pagehttps://github.com/combio-dku
SummaryTookits for Tumor cell identification in single-cell RNA-seq data
upload_time2025-07-15 05:09:01
maintainerNone
docs_urlNone
authorSeokhyun Yoon
requires_pythonNone
licenseMIT License Copyright (c) 2024 Machine Learning & Bioinformatics Lab. Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE.
keywords single-cell omics bioinformatics
VCS
bugtrack_url
requirements No requirements were recorded.
Travis-CI No Travis.
coveralls test coverage No coveralls.
            # InferPloidy
## Brief introduction
- InferPloidy is a CNV-based, ploidy annotation tool for single-cell RNA-seq data.
- It works with the CNV-estimates obtained from [infercnv](https://github.com/icbi-lab/infercnvpy) .

## Cite InferPloidy
- "InferPloidy: A fast ploidy inference tool accurately classifies cells with abnormal CNVs in large single-cell RNA-seq datasets", available at [bioRxiv](https://doi.org/10.1101/2025.03.13.643178) 

<div align="center">
  <img src="https://github.com/combio-dku/inferploidy/blob/main/images/inferploidy.png" style="width:80%;"/>
</div>

## Installation using pip, importing inferploidy in Python

InferPloidy can be installed using pip command. With python3 installed in your system, simply use the follwing command in a terminal.

`pip install inferploidy`

Once it is installed using pip, you can import two functions using the following python command.

`from inferploidy import run_infercnv, run_inferploidy`

## Example usage in Jupyter notebook

`inferPloidy_example.ipynb` is example code in Jupyter notebook, where you can see how to import and run InferPloidy. 

To run HiCAT, you need the pre-installed python packages `numpy`, `pandas`, `scikit-learn`, `scipy`, `scikit-network`, `infercnvpy` and , `hicat`.
`hicat` is used to annotate cell-type to collect reference cells for infercnv.
All of them can be installed simply using `pip` command.

## Contact
Send email to syoon@dku.edu for any inquiry on the usages.


            

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