sequence-alignment-by-cross-correlation


Namesequence-alignment-by-cross-correlation JSON
Version 0.1.0 PyPI version JSON
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home_pagehttps://github.com/kuhjuice/sequence_alignment_by_cross_correlation
SummaryAn implementation of sequence alignment on the basis of cross-correlation technique
upload_time2022-12-25 02:34:43
maintainer
docs_urlNone
authorBo Kern
requires_python>=3.6
licenseMIT license
keywords sequence_alignment_by_cross_correlation
VCS
bugtrack_url
requirements No requirements were recorded.
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coveralls test coverage No coveralls.
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<br />
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  <a href="https://github.com/kuhjuice/sequence_alignment_by_cross_correlation">
    <img style='border-radius:30px' src="images/logo.png" alt="Logo" width="120" height="120">
  </a>

<h3 align="center">Sequence Alignment<br>by cross correlation</h3>

  <p align="center">
    This is an implementation of the cross correlation algorithm for DNA/RNA alignment
    <br />
    <a href="https://github.com/kuhjuice/sequence_alignment_by_cross_correlation"><strong>Explore the docs »</strong></a>
    <br />
    <br />
    <!-- <a href="https://github.com/kuhjuice/sequence_alignment_by_cross_correlation">View Demo</a>
    ·
    -->
    <a href="https://github.com/kuhjuice/sequence_alignment_by_cross_correlation/issues">Report Bug</a>
    ·
    <a href="https://github.com/kuhjuice/sequence_alignment_by_cross_correlation/issues">Request Feature</a>
  </p>
</div>



<!-- TABLE OF CONTENTS -->
<details>
  <summary>Table of Contents</summary>
  <ol>
    <li>
      <a href="#about-the-project">About The Project</a>
      <ul>
        <li><a href="#built-with">Built With</a></li>
      </ul>
    </li>
    <li>
      <a href="#getting-started">Getting Started</a>
      <ul>
        <li><a href="#prerequisites">Prerequisites</a></li>
        <li><a href="#installation">Installation</a></li>
      </ul>
    </li>
    <li><a href="#usage">Usage</a></li>
    <li><a href="#roadmap">Roadmap</a></li>
    <li><a href="#contributing">Contributing</a></li>
    <li><a href="#license">License</a></li>
    <li><a href="#contact">Contact</a></li>
    <li><a href="#acknowledgments">Acknowledgments</a></li>
  </ol>
</details>



<!-- ABOUT THE PROJECT -->
## About The Project
The project is based on the paper [Sequence Alignment by Cross-Correlation](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2291754/) and bridges the gap between the knowledge and an useful implementation. The underlying technique is the cross correlation algorithm, which can be tested in this [notebook](https://makeabilitylab.github.io/physcomp/signals/ComparingSignals/index.html).

Another [notebook](https://colab.research.google.com/drive/1XC0AIqli6igxuDt0phcmZCu5IK5tiV7W?usp=sharing) can be seen here. The focus of this notebook is to illustrate how we can use the cross correlation for genomic data.

The gene sequences were obtained using the [NCBI](https://www.ncbi.nlm.nih.gov/gene/) database.

![Example Screen Shot][product-screenshot]

<!-- Here's a blank template to get started: To avoid retyping too much info. Do a search and replace with your text editor for the following: `kuhjuice`, `sequence_alignment_by_cross_correlation`, `twitter_handle`, `linkedin_username`, `email_client`, `email`, `project_title`, `project_description` -->

<p align="right">(<a href="#readme-top">back to top</a>)</p>

<!-- GETTING STARTED -->
## Getting Started

This is an example of how you may give instructions on setting up your project locally.
To get a local copy up and running follow these simple example steps.

### Prerequisites

This is an example of how to list things you need to use the software and how to install them.
* python3: https://realpython.com/installing-python/

### Installation

1. Clone the repo
   ```sh
   git clone https://github.com/kuhjuice/sequence_alignment_by_cross_correlation.git
   ```
2. Navigate into the repo
   ```sh
   cd sequence_alignment_by_cross_correlation
   ```
3. Install requirements.txt
   ```sh
   pip install -r requirements.txt
   ```
   or
   ```sh
   pip3 install -r requirements.txt
   ```
4. Ask the CLI for help with
   ```sh
   python3 sequence_alignment_by_cross_correlation.py --help
   ```

<p align="right">(<a href="#readme-top">back to top</a>)</p>



<!-- USAGE EXAMPLES -->
## Usage
### Example 1
If we want to get an understanding of what the tool can do for us, we can use the help function of the CLI.
```sh
python3 sequence_alignment_by_cross_correlation/sequence_alignment_by_cross_correlation.py --help
```
![Help Screen Shot][help-screenshot]
### Example 2
If we want to find the gene omcB in the genome of Chlamydia Trachomatis we can use the sequence files in `sequencesToTest`

Executing the following will search for the omcB Gene in the genome of Chlamydia Trachomatis

   ```sh
python3 sequence_alignment_by_cross_correlation/sequence_alignment_by_cross_correlation.py 'sequencesToTest/C_T_genome.fasta' 'sequencesToTest/omcB_C_T_100fit.fna'
   ```

![Usage Screen Shot][usage-screenshot]

<p align="right">(<a href="#readme-top">back to top</a>)</p>



<!-- ROADMAP -->
## Roadmap

- [ ] Fix Bugs
- [ ] Make it a real package
- [ ] Evalueate if useful for other projects

See the [open issues](https://github.com/kuhjuice/sequence_alignment_by_cross_correlation/issues) for a full list of proposed features (and known issues).

<p align="right">(<a href="#readme-top">back to top</a>)</p>



<!-- CONTRIBUTING -->
## Contributing

Contributions are what make the open source community such an amazing place to learn, inspire, and create. Any contributions you make are **greatly appreciated**.

If you have a suggestion that would make this better, please fork the repo and create a pull request. You can also simply open an issue with the tag "enhancement".
Don't forget to give the project a star! Thanks again!

1. Fork the Project
2. Create your Feature Branch (`git checkout -b feature/AmazingFeature`)
3. Commit your Changes (`git commit -m 'Add some AmazingFeature'`)
4. Push to the Branch (`git push origin feature/AmazingFeature`)
5. Open a Pull Request

<p align="right">(<a href="#readme-top">back to top</a>)</p>



<!-- LICENSE -->
## License

Distributed under the MIT License. See `LICENSE.txt` for more information.

<p align="right">(<a href="#readme-top">back to top</a>)</p>



<!-- CONTACT -->
## Contact

Bo Kern - [@blood_in_the_water@chaos.social ](https://chaos.social/@blood_in_the_water) - bo@blackscript.de

Project Link: [https://github.com/kuhjuice/sequence_alignment_by_cross_correlation](https://github.com/kuhjuice/sequence_alignment_by_cross_correlation)

<p align="right">(<a href="#readme-top">back to top</a>)</p>



<!-- ACKNOWLEDGMENTS -->
## Acknowledgments

* [TU-Berlin](tu.berlin)
* [Carmen Regner](https://www.tu.berlin/mikrobiologie/ueber-uns/team-personen/#c422452)

<p align="right">(<a href="#readme-top">back to top</a>)</p>



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The underlying technique is the cross correlation algorithm, which can be tested in this [notebook](https://makeabilitylab.github.io/physcomp/signals/ComparingSignals/index.html).\n\nAnother [notebook](https://colab.research.google.com/drive/1XC0AIqli6igxuDt0phcmZCu5IK5tiV7W?usp=sharing) can be seen here. The focus of this notebook is to illustrate how we can use the cross correlation for genomic data.\n\nThe gene sequences were obtained using the [NCBI](https://www.ncbi.nlm.nih.gov/gene/) database.\n\n![Example Screen Shot][product-screenshot]\n\n<!-- Here's a blank template to get started: To avoid retyping too much info. Do a search and replace with your text editor for the following: `kuhjuice`, `sequence_alignment_by_cross_correlation`, `twitter_handle`, `linkedin_username`, `email_client`, `email`, `project_title`, `project_description` -->\n\n<p align=\"right\">(<a href=\"#readme-top\">back to top</a>)</p>\n\n<!-- GETTING STARTED -->\n## Getting Started\n\nThis is an example of how you may give instructions on setting up your project locally.\nTo get a local copy up and running follow these simple example steps.\n\n### Prerequisites\n\nThis is an example of how to list things you need to use the software and how to install them.\n* python3: https://realpython.com/installing-python/\n\n### Installation\n\n1. Clone the repo\n   ```sh\n   git clone https://github.com/kuhjuice/sequence_alignment_by_cross_correlation.git\n   ```\n2. Navigate into the repo\n   ```sh\n   cd sequence_alignment_by_cross_correlation\n   ```\n3. Install requirements.txt\n   ```sh\n   pip install -r requirements.txt\n   ```\n   or\n   ```sh\n   pip3 install -r requirements.txt\n   ```\n4. Ask the CLI for help with\n   ```sh\n   python3 sequence_alignment_by_cross_correlation.py --help\n   ```\n\n<p align=\"right\">(<a href=\"#readme-top\">back to top</a>)</p>\n\n\n\n<!-- USAGE EXAMPLES -->\n## Usage\n### Example 1\nIf we want to get an understanding of what the tool can do for us, we can use the help function of the CLI.\n```sh\npython3 sequence_alignment_by_cross_correlation/sequence_alignment_by_cross_correlation.py --help\n```\n![Help Screen Shot][help-screenshot]\n### Example 2\nIf we want to find the gene omcB in the genome of Chlamydia Trachomatis we can use the sequence files in `sequencesToTest`\n\nExecuting the following will search for the omcB Gene in the genome of Chlamydia Trachomatis\n\n   ```sh\npython3 sequence_alignment_by_cross_correlation/sequence_alignment_by_cross_correlation.py 'sequencesToTest/C_T_genome.fasta' 'sequencesToTest/omcB_C_T_100fit.fna'\n   ```\n\n![Usage Screen Shot][usage-screenshot]\n\n<p align=\"right\">(<a href=\"#readme-top\">back to top</a>)</p>\n\n\n\n<!-- ROADMAP -->\n## Roadmap\n\n- [ ] Fix Bugs\n- [ ] Make it a real package\n- [ ] Evalueate if useful for other projects\n\nSee the [open issues](https://github.com/kuhjuice/sequence_alignment_by_cross_correlation/issues) for a full list of proposed features (and known issues).\n\n<p align=\"right\">(<a href=\"#readme-top\">back to top</a>)</p>\n\n\n\n<!-- CONTRIBUTING -->\n## Contributing\n\nContributions are what make the open source community such an amazing place to learn, inspire, and create. Any contributions you make are **greatly appreciated**.\n\nIf you have a suggestion that would make this better, please fork the repo and create a pull request. You can also simply open an issue with the tag \"enhancement\".\nDon't forget to give the project a star! Thanks again!\n\n1. Fork the Project\n2. Create your Feature Branch (`git checkout -b feature/AmazingFeature`)\n3. Commit your Changes (`git commit -m 'Add some AmazingFeature'`)\n4. Push to the Branch (`git push origin feature/AmazingFeature`)\n5. Open a Pull Request\n\n<p align=\"right\">(<a href=\"#readme-top\">back to top</a>)</p>\n\n\n\n<!-- LICENSE -->\n## License\n\nDistributed under the MIT License. See `LICENSE.txt` for more information.\n\n<p align=\"right\">(<a href=\"#readme-top\">back to top</a>)</p>\n\n\n\n<!-- CONTACT -->\n## Contact\n\nBo Kern - [@blood_in_the_water@chaos.social ](https://chaos.social/@blood_in_the_water) - bo@blackscript.de\n\nProject Link: [https://github.com/kuhjuice/sequence_alignment_by_cross_correlation](https://github.com/kuhjuice/sequence_alignment_by_cross_correlation)\n\n<p align=\"right\">(<a href=\"#readme-top\">back to top</a>)</p>\n\n\n\n<!-- ACKNOWLEDGMENTS -->\n## Acknowledgments\n\n* [TU-Berlin](tu.berlin)\n* [Carmen Regner](https://www.tu.berlin/mikrobiologie/ueber-uns/team-personen/#c422452)\n\n<p align=\"right\">(<a href=\"#readme-top\">back to top</a>)</p>\n\n\n\n<!-- MARKDOWN LINKS & IMAGES -->\n<!-- https://www.markdownguide.org/basic-syntax/#reference-style-links -->\n[contributors-shield]: https://img.shields.io/github/contributors/kuhjuice/sequence_alignment_by_cross_correlation.svg?style=for-the-badge\n[contributors-url]: https://github.com/kuhjuice/sequence_alignment_by_cross_correlation/graphs/contributors\n[forks-shield]: https://img.shields.io/github/forks/kuhjuice/sequence_alignment_by_cross_correlation.svg?style=for-the-badge\n[forks-url]: https://github.com/kuhjuice/sequence_alignment_by_cross_correlation/network/members\n[stars-shield]: https://img.shields.io/github/stars/kuhjuice/sequence_alignment_by_cross_correlation.svg?style=for-the-badge\n[stars-url]: https://github.com/kuhjuice/sequence_alignment_by_cross_correlation/stargazers\n[issues-shield]: https://img.shields.io/github/issues/kuhjuice/sequence_alignment_by_cross_correlation.svg?style=for-the-badge\n[issues-url]: https://github.com/kuhjuice/sequence_alignment_by_cross_correlation/issues\n[license-shield]: https://img.shields.io/github/license/kuhjuice/sequence_alignment_by_cross_correlation.svg?style=for-the-badge\n[license-url]: https://github.com/kuhjuice/sequence_alignment_by_cross_correlation/blob/master/LICENSE.txt\n[linkedin-shield]: https://img.shields.io/badge/-LinkedIn-black.svg?style=for-the-badge&logo=linkedin&colorB=555\n[linkedin-url]: https://linkedin.com/in/bpbk\n[product-screenshot]: images/productScreenshot.png\n[usage-screenshot]: images/usagescreenshot.png\n[help-screenshot]: images/helpScreenshot.png\n[Next.js]: https://img.shields.io/badge/next.js-000000?style=for-the-badge&logo=nextdotjs&logoColor=white\n[Next-url]: https://nextjs.org/\n[React.js]: https://img.shields.io/badge/React-20232A?style=for-the-badge&logo=react&logoColor=61DAFB\n[React-url]: https://reactjs.org/\n[Vue.js]: https://img.shields.io/badge/Vue.js-35495E?style=for-the-badge&logo=vuedotjs&logoColor=4FC08D\n[Vue-url]: https://vuejs.org/\n[Angular.io]: https://img.shields.io/badge/Angular-DD0031?style=for-the-badge&logo=angular&logoColor=white\n[Angular-url]: https://angular.io/\n[Svelte.dev]: https://img.shields.io/badge/Svelte-4A4A55?style=for-the-badge&logo=svelte&logoColor=FF3E00\n[Svelte-url]: https://svelte.dev/\n[Laravel.com]: https://img.shields.io/badge/Laravel-FF2D20?style=for-the-badge&logo=laravel&logoColor=white\n[Laravel-url]: https://laravel.com\n[Bootstrap.com]: https://img.shields.io/badge/Bootstrap-563D7C?style=for-the-badge&logo=bootstrap&logoColor=white\n[Bootstrap-url]: https://getbootstrap.com\n[JQuery.com]: https://img.shields.io/badge/jQuery-0769AD?style=for-the-badge&logo=jquery&logoColor=white\n[JQuery-url]: https://jquery.com \n",
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