Augusta


NameAugusta JSON
Version 1.0.5 PyPI version JSON
download
home_pagehttps://github.com/JanaMus/Augusta
SummaryPython package for inference of the gene regulatory network and the boolean network using RNA-Seq data.
upload_time2024-01-22 13:48:48
maintainer
docs_urlNone
authorJana Musilova, Zdenek Vafek, Karel Sedlar
requires_python>=3.7, <3.9
licenseMIT
keywords computational biology bioinformatics rna-seq mutual information database boolean network gene regulatory network sbml
VCS
bugtrack_url
requirements pandas numpy scikit-learn bioinfokit Bio docker EcoNameTranslator mygene omnipath urllib3 requests bs4 lxml html5lib networkx easydev colormap ccapi
Travis-CI No Travis.
coveralls test coverage No coveralls.
            Augusta
==========

Python package: From RNA-Seq to the Boolean Network through the Gene Regulatory Network

Documentation and tutorials are available at `augusta.readthedocs.io <https://augusta.readthedocs.io>`_.

Quick Guide
----------------

Dependencies:

- Python 3, versions 3.7 and 3.8
- Docker

**Installation:**

We highly recomment installing and using Augusta in a virtual environment.

.. code-block::

   $ conda create -n Augusta_venv python=3.7 anaconda
   $ conda activate Augusta_venv
   

.. code-block::

   $ pip install Augusta


**Usage:** 

See `Inputs <https://augusta.readthedocs.io/en/latest/User%20guide.html>`_ for details about input files and variables.

.. code-block:: 

   $ python
   >>> import Augusta
   
GRN and BN inference using RNA-Seq:

.. code-block:: 

   >>> Augusta.RNASeq_to_BN(count_table_input = 'MyCT_file.csv', promoter_length = My_number, genbank_file_input = 'MyGB_file.gb', normalization_type = 'My_string', motifs_max_time = My_seconds)

GRN inference using RNA-Seq:

.. code-block:: 

   >>> Augusta.RNASeq_to_GRN(count_table_input = 'MyCT_file.csv', promoter_length = My_number, genbank_file_input = 'MyGB_file.gb', normalization_type = 'My_string', motifs_max_time = My_seconds)


BN inference using GRN:

.. code-block:: 

   >>> Augusta.GRN_to_BN(GRN_input = 'MyGRN_file.csv', promoter_length = My_number, genbank_file_input = 'MyGB_file.gb', add_dbs_info = 'My_string')


GRN refinement:

.. code-block:: 

   >>> Augusta.refineGRN(GRN_input = 'MyGRN_file.csv', genbank_file_input = 'MyGB_file.gb', count_table_input = 'MyCT_file.csv', promoter_length = My_number, motifs_max_time = My_seconds)
   




            

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