changeo

Name	changeo JSON
Version	1.3.0 JSON
	download
home_page	http://changeo.readthedocs.io
Summary	A bioinformatics toolkit for processing high-throughput lymphocyte receptor sequencing data.
upload_time	2022-12-12 00:08:27
maintainer
docs_url	None
author	Namita Gupta, Jason Anthony Vander Heiden
requires_python
license	GNU Affero General Public License 3 (AGPL-3)
keywords	bioinformatics sequencing immunology adaptive immunity immunoglobulin airr-seq rep-seq b cell repertoire analysis adaptive immune receptor repertoires
VCS
bugtrack_url
requirements	No requirements were recorded.
Travis-CI	No Travis.
coveralls test coverage	No coveralls.

            .. image:: https://img.shields.io/pypi/dm/changeo
    :target: https://pypi.org/project/changeo
.. image:: https://img.shields.io/static/v1?label=AIRR-C%20sw-tools%20v1&message=compliant&color=008AFF&labelColor=000000&style=plastic
    :target: https://docs.airr-community.org/en/stable/swtools/airr_swtools_standard.html

Change-O - Repertoire clonal assignment toolkit
================================================================================

Change-O is a collection of tools for processing the output of V(D)J alignment
tools, assigning clonal clusters to immunoglobulin (Ig) sequences, and
reconstructing germline sequences.
 
Dramatic improvements in high-throughput sequencing technologies now enable 
large-scale characterization of Ig repertoires, defined as the collection of
trans-membrane antigen-receptor proteins located on the surface of B cells and
T cells. Change-O is a suite of utilities to facilitate advanced analysis of
Ig and TCR sequences following germline segment assignment. Change-O
handles output from IMGT/HighV-QUEST and IgBLAST, and provides a wide variety of
clustering methods for assigning clonal groups to Ig sequences. Record sorting, 
grouping, and various database manipulation operations are also included.

            

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