clep

Name	clep JSON
Version	0.0.3 JSON
	download
home_page
Summary	A Hybrid Data and Knowledge Driven Framework for Generating Patient Representations
upload_time	2024-03-19 09:51:13
maintainer
docs_url	None
author
requires_python	>=3.7
license	Apache License Version 2.0, January 2004 http://www.apache.org/licenses/ TERMS AND CONDITIONS FOR USE, REPRODUCTION, AND DISTRIBUTION 1. Definitions. "License" shall mean the terms and conditions for use, reproduction, and distribution as defined by Sections 1 through 9 of this document. "Licensor" shall mean the copyright owner or entity authorized by the copyright owner that is granting the License. "Legal Entity" shall mean the union of the acting entity and all other entities that control, are controlled by, or are under common control with that entity. For the purposes of this definition, "control" means (i) the power, direct or indirect, to cause the direction or management of such entity, whether by contract or otherwise, or (ii) ownership of fifty percent (50%) or more of the outstanding shares, or (iii) beneficial ownership of such entity. "You" (or "Your") shall mean an individual or Legal Entity exercising permissions granted by this License. "Source" form shall mean the preferred form for making modifications, including but not limited to software source code, documentation source, and configuration files. "Object" form shall mean any form resulting from mechanical transformation or translation of a Source form, including but not limited to compiled object code, generated documentation, and conversions to other media types. "Work" shall mean the work of authorship, whether in Source or Object form, made available under the License, as indicated by a copyright notice that is included in or attached to the work (an example is provided in the Appendix below). "Derivative Works" shall mean any work, whether in Source or Object form, that is based on (or derived from) the Work and for which the editorial revisions, annotations, elaborations, or other modifications represent, as a whole, an original work of authorship. For the purposes of this License, Derivative Works shall not include works that remain separable from, or merely link (or bind by name) to the interfaces of, the Work and Derivative Works thereof. "Contribution" shall mean any work of authorship, including the original version of the Work and any modifications or additions to that Work or Derivative Works thereof, that is intentionally submitted to Licensor for inclusion in the Work by the copyright owner or by an individual or Legal Entity authorized to submit on behalf of the copyright owner. For the purposes of this definition, "submitted" means any form of electronic, verbal, or written communication sent to the Licensor or its representatives, including but not limited to communication on electronic mailing lists, source code control systems, and issue tracking systems that are managed by, or on behalf of, the Licensor for the purpose of discussing and improving the Work, but excluding communication that is conspicuously marked or otherwise designated in writing by the copyright owner as "Not a Contribution." "Contributor" shall mean Licensor and any individual or Legal Entity on behalf of whom a Contribution has been received by Licensor and subsequently incorporated within the Work. 2. Grant of Copyright License. Subject to the terms and conditions of this License, each Contributor hereby grants to You a perpetual, worldwide, non-exclusive, no-charge, royalty-free, irrevocable copyright license to reproduce, prepare Derivative Works of, publicly display, publicly perform, sublicense, and distribute the Work and such Derivative Works in Source or Object form. 3. Grant of Patent License. Subject to the terms and conditions of this License, each Contributor hereby grants to You a perpetual, worldwide, non-exclusive, no-charge, royalty-free, irrevocable (except as stated in this section) patent license to make, have made, use, offer to sell, sell, import, and otherwise transfer the Work, where such license applies only to those patent claims licensable by such Contributor that are necessarily infringed by their Contribution(s) alone or by combination of their Contribution(s) with the Work to which such Contribution(s) was submitted. If You institute patent litigation against any entity (including a cross-claim or counterclaim in a lawsuit) alleging that the Work or a Contribution incorporated within the Work constitutes direct or contributory patent infringement, then any patent licenses granted to You under this License for that Work shall terminate as of the date such litigation is filed. 4. Redistribution. You may reproduce and distribute copies of the Work or Derivative Works thereof in any medium, with or without modifications, and in Source or Object form, provided that You meet the following conditions: (a) You must give any other recipients of the Work or Derivative Works a copy of this License; and (b) You must cause any modified files to carry prominent notices stating that You changed the files; and (c) You must retain, in the Source form of any Derivative Works that You distribute, all copyright, patent, trademark, and attribution notices from the Source form of the Work, excluding those notices that do not pertain to any part of the Derivative Works; and (d) If the Work includes a "NOTICE" text file as part of its distribution, then any Derivative Works that You distribute must include a readable copy of the attribution notices contained within such NOTICE file, excluding those notices that do not pertain to any part of the Derivative Works, in at least one of the following places: within a NOTICE text file distributed as part of the Derivative Works; within the Source form or documentation, if provided along with the Derivative Works; or, within a display generated by the Derivative Works, if and wherever such third-party notices normally appear. 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You are solely responsible for determining the appropriateness of using or redistributing the Work and assume any risks associated with Your exercise of permissions under this License. 8. Limitation of Liability. In no event and under no legal theory, whether in tort (including negligence), contract, or otherwise, unless required by applicable law (such as deliberate and grossly negligent acts) or agreed to in writing, shall any Contributor be liable to You for damages, including any direct, indirect, special, incidental, or consequential damages of any character arising as a result of this License or out of the use or inability to use the Work (including but not limited to damages for loss of goodwill, work stoppage, computer failure or malfunction, or any and all other commercial damages or losses), even if such Contributor has been advised of the possibility of such damages. 9. Accepting Warranty or Additional Liability. While redistributing the Work or Derivative Works thereof, You may choose to offer, and charge a fee for, acceptance of support, warranty, indemnity, or other liability obligations and/or rights consistent with this License. However, in accepting such obligations, You may act only on Your own behalf and on Your sole responsibility, not on behalf of any other Contributor, and only if You agree to indemnify, defend, and hold each Contributor harmless for any liability incurred by, or claims asserted against, such Contributor by reason of your accepting any such warranty or additional liability. END OF TERMS AND CONDITIONS APPENDIX: How to apply the Apache License to your work. To apply the Apache License to your work, attach the following boilerplate notice, with the fields enclosed by brackets "{}" replaced with your own identifying information. (Don't include the brackets!) The text should be enclosed in the appropriate comment syntax for the file format. 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keywords	bioinformatics machine learning prediction models embeddings
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            <p align="center">
  <img src="docs/source/logo.jpg">
</p>

<h1 align="center">
  CLEP: A Hybrid Data- and Knowledge- Driven Framework for Generating Patient Representations
  <br/>
  <a href='https://travis-ci.com/github/hybrid-kg'>
     <img src="https://travis-ci.com/hybrid-kg/clep.svg?branch=master" />
  </a>
  <a href='https://clep.readthedocs.io/en/latest/?badge=latest'>
    <img src='https://readthedocs.org/projects/clep/badge/?version=latest' alt='Documentation Status' />
  </a>
  <a href="https://zenodo.org/badge/latestdoi/209278408">
    <img src="https://zenodo.org/badge/209278408.svg" alt="DOI">
  </a>
  <a href="https://pypi.org/project/clep/">
    <img src="https://img.shields.io/pypi/v/clep" alt="CLEP on PyPI">
  </a>
  <img src="https://img.shields.io/pypi/pyversions/clep" alt="CLEP Python versions">
  <a href="https://github.com/hybrid-kg/clep/blob/master/LICENSE">
    <img src="https://img.shields.io/pypi/l/clep" alt="CLEP Software License">
  </a>
</h1>

## Table of Contents

* [General Info](#general-info)
* [Installation](#installation)
* [Documentation](#documentation)
* [Input Data](#input-data-formats)
* [Usage](#usage)
* [Issues](#issues)
* [Acknowledgements](#acknowledgements)
* [Citation](#citation)
* [Disclaimer](#disclaimer)

## General Info

CLEP is a framework that contains novel methods for generating patient representations from any patient level data and its corresponding prior knowledge encoded in a knowledge graph. The framework is depicted in the graphic below

<p align="center">
  <img src="docs/source/framework.jpg">
</p>

## Installation

The code can be installed from [PyPI](https://pypi.org/project/clep/) with:

```bash
$ pip install clep
```

The most recent code can be installed from the source on [GitHub](https://github.com/hybrid-kg/clep) with:

```bash
$ pip install git+https://github.com/hybrid-kg/clep.git
```

For developers, the repository can be cloned from [GitHub](https://github.com/hybrid-kg/clep) and installed in editable mode with:

```bash
$ git clone https://github.com/hybrid-kg/clep.git
$ cd clep
$ pip install -e .
```

## Documentation

Read the [official docs](https://clep.readthedocs.io/en/latest/) for more information.

## Input Data Formats

### Data

| Symbol | Sample_1 | Sample_2 | Sample_3 |
| ------ | -------- | -------- | -------- |
| HGNC_ID_1 | 0.354 | 2.568 | 1.564 |
| HGNC_ID_2 | 1.255 | 1.232 | 0.26452 |
| HGNC_ID_3 | 3.256 | 1.5 | 1.5462 |

**Note:** The data must be in a tab separated file format.

### Design

| FileName | Target |
| -------- | ------ |
| Sample_1 | Abnormal |
| Sample_2 | Abnormal |
| Sample_3 | Control |

**Note:** The data must be in a tab separated file format.

### Knowledge Graph

The graph format CLEP can handle is a modified version of the Edge List Format. Which looks as follows:

| Source | Relation | Target |
| ------ | -------- | ------ |
| HGNC_ID_1 | association | HGNC_ID_2
| HGNC_ID_2 | decreases | HGNC_ID_3
| HGNC_ID_3 | increases | HGNC_ID_1
    
**Note:** The data must be in a tab separated file format & if your knowledge graph does not have relations between the source and the target, just populate the relation column with "No Relation".


## Usage

**Note:** These are very basic commands for clep, and the detailed options for each command can be found in the [documentation](#documentation)

1. **Radical Searching**
The following command finds the extreme samples with extreme feature values based on the control population.

```bash
$ clep sample-scoring radical-search --data <DATA_FILE> --design <DESIGN_FILE> --control Control --threshold 2.5 --control_based --ret_summary --out <OUTPUT_DIR>
```

2. **Graph Generation**
The following command generates the patient-gene network based on the method chosen (Interaction_network).

```bash
$ clep embedding generate-network --data <SCORED_DATA_FILE> --method interaction_network --ret_summary --out <OUTPUT_DIR>
```

3. **Knowledge Graph Embedding**

The following command generates the embedding of the network passed to it.

```bash
$ clep embedding kge --data <NETWORK_FILE> --design <DESIGN_FILE> --model_config <MODEL_CONFIG.json> --train_size 0.8 --validation_size 0.1 --out <OUTPUT_DIR>
```

4. **Classification**

The following command carries out classification on the given data file for a chosen model (Elastic Net) using a chosen optimizer (Grid Search).

```bash
$ clep classify --data <EMBEDDING_FILE> --model elastic_net --optimizer grid_search --out <OUTPUT_DIR>
```

## Issues

If you have difficulties using CLEP, please open an issue at our [GitHub](https://github.com/hybrid-kg/clep) repository.

## Acknowledgements

### Citation

If you have found CLEP useful in your work, please consider citing:

[**CLEP: A Hybrid Data- and Knowledge- Driven Framework for Generating Patient Representations**](https://doi.org/10.1093/bioinformatics/btab340
).<br />
Bharadhwaj, V. S., Ali, M., Birkenbihl, C., Mubeen, S., Lehmann, J., Hofmann-Apitius, M., Hoyt, C. T., & Domingo-Fernandez, D. (2020).<br />
*Bioinformatics*, btab340. 

### Graphics

The CLEP logo and framework graphic was designed by Carina Steinborn.

## Disclaimer

CLEP is a scientific software that has been developed in an academic capacity, and thus comes with no warranty or guarantee of maintenance, support, or back-up of data.

            

Raw data

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    "keywords": "Bioinformatics,Machine Learning,Prediction Models,Embeddings",
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    "author_email": "Vinay Bharadhwaj <vinay.srinivas.bharadhwaj@scai.fraunhofer.de>",
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    "description": "<p align=\"center\">\n  <img src=\"docs/source/logo.jpg\">\n</p>\n\n<h1 align=\"center\">\n  CLEP: A Hybrid Data- and Knowledge- Driven Framework for Generating Patient Representations\n  <br/>\n  <a href='https://travis-ci.com/github/hybrid-kg'>\n     <img src=\"https://travis-ci.com/hybrid-kg/clep.svg?branch=master\" />\n  </a>\n  <a href='https://clep.readthedocs.io/en/latest/?badge=latest'>\n    <img src='https://readthedocs.org/projects/clep/badge/?version=latest' alt='Documentation Status' />\n  </a>\n  <a href=\"https://zenodo.org/badge/latestdoi/209278408\">\n    <img src=\"https://zenodo.org/badge/209278408.svg\" alt=\"DOI\">\n  </a>\n  <a href=\"https://pypi.org/project/clep/\">\n    <img src=\"https://img.shields.io/pypi/v/clep\" alt=\"CLEP on PyPI\">\n  </a>\n  <img src=\"https://img.shields.io/pypi/pyversions/clep\" alt=\"CLEP Python versions\">\n  <a href=\"https://github.com/hybrid-kg/clep/blob/master/LICENSE\">\n    <img src=\"https://img.shields.io/pypi/l/clep\" alt=\"CLEP Software License\">\n  </a>\n</h1>\n\n## Table of Contents\n\n* [General Info](#general-info)\n* [Installation](#installation)\n* [Documentation](#documentation)\n* [Input Data](#input-data-formats)\n* [Usage](#usage)\n* [Issues](#issues)\n* [Acknowledgements](#acknowledgements)\n* [Citation](#citation)\n* [Disclaimer](#disclaimer)\n\n## General Info\n\nCLEP is a framework that contains novel methods for generating patient representations from any patient level data and its corresponding prior knowledge encoded in a knowledge graph. The framework is depicted in the graphic below\n\n<p align=\"center\">\n  <img src=\"docs/source/framework.jpg\">\n</p>\n\n## Installation\n\nThe code can be installed from [PyPI](https://pypi.org/project/clep/) with:\n\n```bash\n$ pip install clep\n```\n\nThe most recent code can be installed from the source on [GitHub](https://github.com/hybrid-kg/clep) with:\n\n```bash\n$ pip install git+https://github.com/hybrid-kg/clep.git\n```\n\nFor developers, the repository can be cloned from [GitHub](https://github.com/hybrid-kg/clep) and installed in editable mode with:\n\n```bash\n$ git clone https://github.com/hybrid-kg/clep.git\n$ cd clep\n$ pip install -e .\n```\n\n## Documentation\n\nRead the [official docs](https://clep.readthedocs.io/en/latest/) for more information.\n\n## Input Data Formats\n\n### Data\n\n| Symbol | Sample_1 | Sample_2 | Sample_3 |\n| ------ | -------- | -------- | -------- |\n| HGNC_ID_1 | 0.354 | 2.568 | 1.564 |\n| HGNC_ID_2 | 1.255 | 1.232 | 0.26452 |\n| HGNC_ID_3 | 3.256 | 1.5 | 1.5462 |\n\n**Note:** The data must be in a tab separated file format.\n\n### Design\n\n| FileName | Target |\n| -------- | ------ |\n| Sample_1 | Abnormal |\n| Sample_2 | Abnormal |\n| Sample_3 | Control |\n\n**Note:** The data must be in a tab separated file format.\n\n### Knowledge Graph\n\nThe graph format CLEP can handle is a modified version of the Edge List Format. Which looks as follows:\n\n| Source | Relation | Target |\n| ------ | -------- | ------ |\n| HGNC_ID_1 | association | HGNC_ID_2\n| HGNC_ID_2 | decreases | HGNC_ID_3\n| HGNC_ID_3 | increases | HGNC_ID_1\n    \n**Note:** The data must be in a tab separated file format & if your knowledge graph does not have relations between the source and the target, just populate the relation column with \"No Relation\".\n\n\n## Usage\n\n**Note:** These are very basic commands for clep, and the detailed options for each command can be found in the [documentation](#documentation)\n\n1. **Radical Searching**\nThe following command finds the extreme samples with extreme feature values based on the control population.\n\n```bash\n$ clep sample-scoring radical-search --data <DATA_FILE> --design <DESIGN_FILE> --control Control --threshold 2.5 --control_based --ret_summary --out <OUTPUT_DIR>\n```\n\n2. **Graph Generation**\nThe following command generates the patient-gene network based on the method chosen (Interaction_network).\n\n```bash\n$ clep embedding generate-network --data <SCORED_DATA_FILE> --method interaction_network --ret_summary --out <OUTPUT_DIR>\n```\n\n3. **Knowledge Graph Embedding**\n\nThe following command generates the embedding of the network passed to it.\n\n```bash\n$ clep embedding kge --data <NETWORK_FILE> --design <DESIGN_FILE> --model_config <MODEL_CONFIG.json> --train_size 0.8 --validation_size 0.1 --out <OUTPUT_DIR>\n```\n\n4. **Classification**\n\nThe following command carries out classification on the given data file for a chosen model (Elastic Net) using a chosen optimizer (Grid Search).\n\n```bash\n$ clep classify --data <EMBEDDING_FILE> --model elastic_net --optimizer grid_search --out <OUTPUT_DIR>\n```\n\n## Issues\n\nIf you have difficulties using CLEP, please open an issue at our [GitHub](https://github.com/hybrid-kg/clep) repository.\n\n## Acknowledgements\n\n### Citation\n\nIf you have found CLEP useful in your work, please consider citing:\n\n[**CLEP: A Hybrid Data- and Knowledge- Driven Framework for Generating Patient Representations**](https://doi.org/10.1093/bioinformatics/btab340\n).<br />\nBharadhwaj, V. S., Ali, M., Birkenbihl, C., Mubeen, S., Lehmann, J., Hofmann-Apitius, M., Hoyt, C. T., & Domingo-Fernandez, D. (2020).<br />\n*Bioinformatics*, btab340. \n\n### Graphics\n\nThe CLEP logo and framework graphic was designed by Carina Steinborn.\n\n## Disclaimer\n\nCLEP is a scientific software that has been developed in an academic capacity, and thus comes with no warranty or guarantee of maintenance, support, or back-up of data.\n",
    "bugtrack_url": null,
    "license": "Apache License Version 2.0, January 2004 http://www.apache.org/licenses/  TERMS AND CONDITIONS FOR USE, REPRODUCTION, AND DISTRIBUTION  1. Definitions.  \"License\" shall mean the terms and conditions for use, reproduction, and distribution as defined by Sections 1 through 9 of this document.  \"Licensor\" shall mean the copyright owner or entity authorized by the copyright owner that is granting the License.  \"Legal Entity\" shall mean the union of the acting entity and all other entities that control, are controlled by, or are under common control with that entity. For the purposes of this definition, \"control\" means (i) the power, direct or indirect, to cause the direction or management of such entity, whether by contract or otherwise, or (ii) ownership of fifty percent (50%) or more of the outstanding shares, or (iii) beneficial ownership of such entity.  \"You\" (or \"Your\") shall mean an individual or Legal Entity exercising permissions granted by this License.  \"Source\" form shall mean the preferred form for making modifications, including but not limited to software source code, documentation source, and configuration files.  \"Object\" form shall mean any form resulting from mechanical transformation or translation of a Source form, including but not limited to compiled object code, generated documentation, and conversions to other media types.  \"Work\" shall mean the work of authorship, whether in Source or Object form, made available under the License, as indicated by a copyright notice that is included in or attached to the work (an example is provided in the Appendix below).  \"Derivative Works\" shall mean any work, whether in Source or Object form, that is based on (or derived from) the Work and for which the editorial revisions, annotations, elaborations, or other modifications represent, as a whole, an original work of authorship. For the purposes of this License, Derivative Works shall not include works that remain separable from, or merely link (or bind by name) to the interfaces of, the Work and Derivative Works thereof.  \"Contribution\" shall mean any work of authorship, including the original version of the Work and any modifications or additions to that Work or Derivative Works thereof, that is intentionally submitted to Licensor for inclusion in the Work by the copyright owner or by an individual or Legal Entity authorized to submit on behalf of the copyright owner. For the purposes of this definition, \"submitted\" means any form of electronic, verbal, or written communication sent to the Licensor or its representatives, including but not limited to communication on electronic mailing lists, source code control systems, and issue tracking systems that are managed by, or on behalf of, the Licensor for the purpose of discussing and improving the Work, but excluding communication that is conspicuously marked or otherwise designated in writing by the copyright owner as \"Not a Contribution.\"  \"Contributor\" shall mean Licensor and any individual or Legal Entity on behalf of whom a Contribution has been received by Licensor and subsequently incorporated within the Work.  2. Grant of Copyright License. Subject to the terms and conditions of this License, each Contributor hereby grants to You a perpetual, worldwide, non-exclusive, no-charge, royalty-free, irrevocable copyright license to reproduce, prepare Derivative Works of, publicly display, publicly perform, sublicense, and distribute the Work and such Derivative Works in Source or Object form.  3. Grant of Patent License. Subject to the terms and conditions of this License, each Contributor hereby grants to You a perpetual, worldwide, non-exclusive, no-charge, royalty-free, irrevocable (except as stated in this section) patent license to make, have made, use, offer to sell, sell, import, and otherwise transfer the Work, where such license applies only to those patent claims licensable by such Contributor that are necessarily infringed by their Contribution(s) alone or by combination of their Contribution(s) with the Work to which such Contribution(s) was submitted. If You institute patent litigation against any entity (including a cross-claim or counterclaim in a lawsuit) alleging that the Work or a Contribution incorporated within the Work constitutes direct or contributory patent infringement, then any patent licenses granted to You under this License for that Work shall terminate as of the date such litigation is filed.  4. Redistribution. You may reproduce and distribute copies of the Work or Derivative Works thereof in any medium, with or without modifications, and in Source or Object form, provided that You meet the following conditions:  (a) You must give any other recipients of the Work or Derivative Works a copy of this License; and  (b) You must cause any modified files to carry prominent notices stating that You changed the files; and  (c) You must retain, in the Source form of any Derivative Works that You distribute, all copyright, patent, trademark, and attribution notices from the Source form of the Work, excluding those notices that do not pertain to any part of the Derivative Works; and  (d) If the Work includes a \"NOTICE\" text file as part of its distribution, then any Derivative Works that You distribute must include a readable copy of the attribution notices contained within such NOTICE file, excluding those notices that do not pertain to any part of the Derivative Works, in at least one of the following places: within a NOTICE text file distributed as part of the Derivative Works; within the Source form or documentation, if provided along with the Derivative Works; or, within a display generated by the Derivative Works, if and wherever such third-party notices normally appear. The contents of the NOTICE file are for informational purposes only and do not modify the License. You may add Your own attribution notices within Derivative Works that You distribute, alongside or as an addendum to the NOTICE text from the Work, provided that such additional attribution notices cannot be construed as modifying the License.  You may add Your own copyright statement to Your modifications and may provide additional or different license terms and conditions for use, reproduction, or distribution of Your modifications, or for any such Derivative Works as a whole, provided Your use, reproduction, and distribution of the Work otherwise complies with the conditions stated in this License.  5. Submission of Contributions. Unless You explicitly state otherwise, any Contribution intentionally submitted for inclusion in the Work by You to the Licensor shall be under the terms and conditions of this License, without any additional terms or conditions. Notwithstanding the above, nothing herein shall supersede or modify the terms of any separate license agreement you may have executed with Licensor regarding such Contributions.  6. Trademarks. This License does not grant permission to use the trade names, trademarks, service marks, or product names of the Licensor, except as required for reasonable and customary use in describing the origin of the Work and reproducing the content of the NOTICE file.  7. Disclaimer of Warranty. Unless required by applicable law or agreed to in writing, Licensor provides the Work (and each Contributor provides its Contributions) on an \"AS IS\" BASIS, WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied, including, without limitation, any warranties or conditions of TITLE, NON-INFRINGEMENT, MERCHANTABILITY, or FITNESS FOR A PARTICULAR PURPOSE. You are solely responsible for determining the appropriateness of using or redistributing the Work and assume any risks associated with Your exercise of permissions under this License.  8. Limitation of Liability. In no event and under no legal theory, whether in tort (including negligence), contract, or otherwise, unless required by applicable law (such as deliberate and grossly negligent acts) or agreed to in writing, shall any Contributor be liable to You for damages, including any direct, indirect, special, incidental, or consequential damages of any character arising as a result of this License or out of the use or inability to use the Work (including but not limited to damages for loss of goodwill, work stoppage, computer failure or malfunction, or any and all other commercial damages or losses), even if such Contributor has been advised of the possibility of such damages.  9. Accepting Warranty or Additional Liability. While redistributing the Work or Derivative Works thereof, You may choose to offer, and charge a fee for, acceptance of support, warranty, indemnity, or other liability obligations and/or rights consistent with this License. However, in accepting such obligations, You may act only on Your own behalf and on Your sole responsibility, not on behalf of any other Contributor, and only if You agree to indemnify, defend, and hold each Contributor harmless for any liability incurred by, or claims asserted against, such Contributor by reason of your accepting any such warranty or additional liability.  END OF TERMS AND CONDITIONS  APPENDIX: How to apply the Apache License to your work.  To apply the Apache License to your work, attach the following boilerplate notice, with the fields enclosed by brackets \"{}\" replaced with your own identifying information. (Don't include the brackets!)  The text should be enclosed in the appropriate comment syntax for the file format. We also recommend that a file or class name and description of purpose be included on the same \"printed page\" as the copyright notice for easier identification within third-party archives.  Copyright 2019-2020 Vinay Srinivas Bharadhwaj  Licensed under the Apache License, Version 2.0 (the \"License\"); you may not use this file except in compliance with the License. You may obtain a copy of the License at  http://www.apache.org/licenses/LICENSE-2.0  Unless required by applicable law or agreed to in writing, software distributed under the License is distributed on an \"AS IS\" BASIS, WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied. See the License for the specific language governing permissions and limitations under the License. ",
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