multiqc-xenium-extra


Namemultiqc-xenium-extra JSON
Version 1.0.1 PyPI version JSON
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home_pageNone
SummaryMultiQC plugin for extra Xenium spatial transcriptomics analysis
upload_time2025-10-25 22:17:27
maintainerNone
docs_urlNone
authorNone
requires_python>=3.9
licenseMIT License Copyright (c) 2024 Phil Ewels Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE.
keywords bioinformatics biology spatial transcriptomics xenium quality control
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            # MultiQC Xenium Extra Plugin

Advanced analysis plugin for Xenium spatial transcriptomics data in MultiQC.

This plugin extends the core MultiQC Xenium module with computationally intensive analyses including:

- Parquet file processing (transcripts.parquet, cells.parquet)
- H5 matrix analysis (cell_feature_matrix.h5)
- Distribution plots (density, violin, box plots)
- Cell area and nucleus analysis
- Transcript quality distributions
- FoV quality heatmaps

## Installation

```bash
pip install multiqc-xenium-extra
```

## Requirements

- MultiQC >= 1.20
- polars >= 0.18.0
- scipy >= 1.8.0
- scanpy >= 1.9.0

## Configuration

The plugin automatically adjusts the file size limit to handle large Xenium files:

```yaml
log_filesize_limit: 5000000000 # 5GB
```

## Usage

Once installed, the plugin automatically extends the Xenium module when you run MultiQC:

```bash
multiqc /path/to/xenium/data
```

The extra sections will appear alongside the core Xenium module sections in the report.

            

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