pyGeneEnrich


NamepyGeneEnrich JSON
Version 0.0.2 PyPI version JSON
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home_pageNone
SummaryA limited python implementation of clusterProfiler from R
upload_time2024-04-07 07:33:45
maintainerNone
docs_urlNone
authorWhiteRabBio
requires_python>=3.9
licenseMIT License Copyright (c) 2024 WhiteRabBio Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE.
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VCS
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requirements pandas numpy scipy statsmodels
Travis-CI No Travis.
coveralls test coverage No coveralls.
            GeneEnrich
==========

Installation and Usage
----------------------

##### Manual installation (Without Update Database Function)

~~~~~~~~~~~~~~~~~~~bash

The recommended installation is as follows:

.. code-block:: bash

   (GeneEnrich) $ pip install GeneEnrich

~~~~~~~~~~~~~~~~~~~

##### Manual installation

~~~~~~~~~~~~~~~~~~~bash
The recommended installation is as follows:
conda_pkgs.txt can be found in https://github.com/WhiteRabBio/GeneEnrich

.. code-block:: bash

   (GeneEnrich) $ mamba create -n GeneEnrich -y --file conda_pkgs.txt
   (GeneEnrich) $ pip install GeneEnrich

~~~~~~~~~~~~~~~~~~~

##### Usage

```bash
usage: GeneEnrich run_go [-h] --input INPUT_FILE --prefix PREFIX --output OUTPUT_DIR --species SPECIES --type
                         {scanpy_deg,seuratv3_deg,seuratv4_deg,list} [--updown {up,down,both}] [--pvalue PVALUE] [--qvalue QVALUE]

Run enrichment based on GO database.

options:
  -h, --help            show this help message and exit
  --input INPUT_FILE    Choosen from `Differential Expression Gene file generated by Scanpy or Seurat` And `One column gene list
  --prefix PREFIX       Prefix of output results.
  --output OUTPUT_DIR   Output file location.
  --species SPECIES     Support human or mouse.
  --type {scanpy_deg,seuratv3_deg,seuratv4_deg,list}
                        DEG file or Gene list file
  --updown {up,down,both}
                        Use up-regulated gene\down-regulated gene\ both, if DEG provided.
  --pvalue PVALUE       Pvalue cutoff for enrichment
  --qvalue QVALUE       Qvalue cutoff for enrichment

```



```bash
usage: GeneEnrich run_kegg [-h] --input INPUT_FILE --prefix PREFIX --output OUTPUT_DIR --species SPECIES --type
                           {scanpy_deg,seuratv3_deg,seuratv4_deg,list} [--updown {up,down,both}] [--pvalue PVALUE] [--qvalue QVALUE]

Run enrichment based on KEGG database.

options:
  -h, --help            show this help message and exit
  --input INPUT_FILE    Choosen from `Differential Expression Gene file generated by Scanpy or Seurat` And `One column gene list
  --prefix PREFIX       Prefix of output results.
  --output OUTPUT_DIR   Output file location.
  --species SPECIES     Support human or mouse.
  --type {scanpy_deg,seuratv3_deg,seuratv4_deg,list}
                        DEG file or Gene list file
  --updown {up,down,both}
                        Use up-regulated gene\down-regulated gene\ both, if DEG provided.
  --pvalue PVALUE       Pvalue cutoff for enrichment
  --qvalue QVALUE       Qvalue cutoff for enrichment

```



```bash
usage: GeneEnrich update_db [-h] --database {KEGG,GO} --species SPECIES --version {python,R}

Update GO and KEGG database.

options:
  -h, --help            show this help message and exit
  --database {KEGG,GO}  Choosen from KEGG or GO database to update.
  --species SPECIES     Support human or mouse.
  --version {python,R}  If python, will download latest database from website. If R, will extract database from existing database
                        info.
```



##### Citation

Yu, Guangchuang et al. “clusterProfiler: an R package for comparing biological themes among gene clusters.” *Omics : a journal of integrative biology* vol. 16,5 (2012): 284-7. doi:10.1089/omi.2011.0118

            

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